InnateDB Protein
|
IDBP-28963.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
ARPC1B
|
Protein Name
|
actin related protein 2/3 complex, subunit 1B, 41kDa
|
Synonyms
|
ARC41; p40-ARC; p41-ARC;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000252725
|
InnateDB Gene
|
IDBG-28961 (ARPC1B)
|
Protein Structure
|
|
Function |
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
|
Subcellular Localization |
Cytoplasm, cytoskeleton.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
62
[view]
|
Protein-Protein |
62
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
2 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001680
WD40 repeat
IPR017383
ARP2/3 complex, 41kDa subunit (p41-arc)
IPR017986
WD40-repeat-containing domain
|
PFAM |
PF00400
|
PRINTS |
|
PIRSF |
PIRSF038093
|
SMART |
SM00320
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O15143
|
PhosphoSite |
PhosphoSite-O15143
|
TrEMBL |
F8VXW2
|
UniProt Splice Variant |
|
Entrez Gene |
10095
|
UniGene |
|
RefSeq |
NP_005711
|
HUGO |
HGNC:704
|
OMIM |
604223
|
CCDS |
CCDS5661
|
HPRD |
10366
|
IMGT |
|
EMBL |
AC004922
AF006084
AK314818
BC002562
BC002988
BC007555
CH236956
CH471091
|
GenPept |
AAB64189
AAH02562
AAH02988
AAH07555
BAG37341
EAL23882
EAW76677
EAW76678
EAW76679
EAW76680
|
|
|