InnateDB Protein
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IDBP-29234.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATP5J2
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Protein Name
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ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
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Synonyms
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ATP5JL;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000292475
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InnateDB Gene
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IDBG-409428 (ATP5J2)
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Protein Structure
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Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
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Subcellular Localization |
Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
24
[view]
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Protein-Protein |
23
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR019344
Mitochondrial F1-F0 ATP synthase subunit F, predicted
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PFAM |
PF10206
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P56134
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PhosphoSite |
PhosphoSite-P56134
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9551
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UniGene |
Hs.710672
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RefSeq |
NP_004880
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HUGO |
HGNC:848
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OMIM |
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CCDS |
CCDS5665
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HPRD |
16520
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IMGT |
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EMBL |
AC073063
AF047436
AF088918
AY046911
BC003678
CH236956
CH471091
CR456891
CR542155
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GenPept |
AAC34895
AAC39887
AAH03678
AAL06647
CAG33172
CAG46952
EAL23877
EAW76661
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