InnateDB Protein
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IDBP-2924.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PRMT5
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Protein Name
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protein arginine methyltransferase 5
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Synonyms
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HRMT1L5; IBP72; JBP1; SKB1; SKB1Hs;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000216350
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InnateDB Gene
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IDBG-2920 (PRMT5)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 217 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated |
Total |
217
[view]
|
Protein-Protein |
211
[view]
|
Protein-DNA |
6
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
21 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0001046
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core promoter sequence-specific DNA binding
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GO:0003714
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transcription corepressor activity
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GO:0005515
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protein binding
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GO:0008168
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methyltransferase activity
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GO:0008469
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histone-arginine N-methyltransferase activity
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GO:0035243
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protein-arginine omega-N symmetric methyltransferase activity
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GO:0043021
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ribonucleoprotein complex binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007857
Protein arginine N-methyltransferase PRMT5
IPR025799
Protein arginine N-methyltransferase
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
|
PFAM |
PF05185
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PRINTS |
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PIRSF |
PIRSF015894
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O14744
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PhosphoSite |
PhosphoSite-O14744
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TrEMBL |
G3V5T6
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UniProt Splice Variant |
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Entrez Gene |
10419
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UniGene |
Hs.367854
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RefSeq |
NP_001269883
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HUGO |
HGNC:10894
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OMIM |
604045
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CCDS |
CCDS61394
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HPRD |
04955
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IMGT |
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EMBL |
AB451246
AB451370
AF015913
AF167572
AK075251
AK301812
AK302240
AL132780
BC005820
BC025979
CH471078
CR456741
|
GenPept |
AAB66581
AAF04502
AAH25979
BAG52095
BAG63261
BAG63592
BAG70060
BAG70184
CAG33022
EAW66218
EAW66219
EAW66220
EAW66221
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