InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SWSAP1

Summary

InnateDB Protein

IDBP-29253.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SWSAP1

Protein Name

chromosome 19 open reading frame 39

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000310008

InnateDB Gene

IDBG-29251 (SWSAP1)

Protein Structure

UniProt Annotation

Function

ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity. {ECO:0000269PubMed:21965664}.

Subcellular Localization

Nucleus {ECO:0000305PubMed:21965664}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0016887	ATPase activity

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006200	ATP catabolic process
GO:0050821	protein stabilization

Cellular Component

GO:0005634	nucleus
GO:0097196	Shu complex

Protein Structure and Domains

PDB ID

InterPro

IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6NVH7

PhosphoSite

PhosphoSite-Q6NVH7

TrEMBL

UniProt Splice Variant

Entrez Gene

126074

UniGene

Hs.631619

RefSeq

NP_787067

HUGO

HGNC:26638

OMIM

614536

CCDS

CCDS12259

HPRD

08179

IMGT

EMBL

AC024575 AK092438 BC068071 BC119677

GenPept

AAH68071 AAI19678 BAC03891