InnateDB Protein
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IDBP-29372.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZDHHC3
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Protein Name
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zinc finger, DHHC-type containing 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000296127
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InnateDB Gene
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IDBG-29370 (ZDHHC3)
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Protein Structure
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Function |
Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity). {ECO:0000250}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001594
Zinc finger, DHHC-type, palmitoyltransferase
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PFAM |
PF01529
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NYG2
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PhosphoSite |
PhosphoSite-Q9NYG2
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TrEMBL |
C9JNU5
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UniProt Splice Variant |
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Entrez Gene |
51304
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UniGene |
Hs.61430
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RefSeq |
NP_057682
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HUGO |
HGNC:18470
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OMIM |
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CCDS |
CCDS2724
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HPRD |
15718
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IMGT |
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EMBL |
AC098649
AC104165
AF247703
AF441791
AY605661
BC015467
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GenPept |
AAF63570
AAH15467
AAL34547
AAV83779
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