Version 5.4
Homo sapiens Protein: TSC1
Summary
InnateDB Protein IDBP-294284.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSC1
Protein Name tuberous sclerosis 1
Synonyms LAM; TSC;
Species Homo sapiens
Ensembl Protein ENSP00000386093
InnateDB Gene IDBG-90470 (TSC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 105 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 105 [view]
Protein-Protein 103 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007483 Hamartin
IPR016024 Armadillo-type fold
PFAM PF04388
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q86WV8
UniProt Splice Variant
Entrez Gene 7248
UniGene Hs.713977
RefSeq
HUGO HGNC:12362
OMIM 605284
CCDS
HPRD 05594
IMGT
EMBL AL445645 BC047772 BC070032
GenPept AAH47772 AAH70032

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca