Version 5.4
Homo sapiens Protein: TBC1D8
Summary
InnateDB Protein IDBP-295143.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D8
Protein Name TBC1 domain family, member 8 (with GRAM domain)
Synonyms AD3; HBLP1; TBC1D8A; VRP;
Species Homo sapiens
Ensembl Protein ENSP00000386856
InnateDB Gene IDBG-63709 (TBC1D8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR004182 GRAM domain
PFAM PF00566
PF02893
PRINTS
PIRSF
SMART SM00164
SM00568
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3KQ40
UniProt Splice Variant
Entrez Gene 11138
UniGene Hs.442657
RefSeq XP_005263919
HUGO HGNC:17791
OMIM
CCDS
HPRD 06752
IMGT
EMBL AC013722 AC016738
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca