Version 5.4
Homo sapiens Protein: ITFG1
Summary
InnateDB Protein IDBP-29558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITFG1
Protein Name integrin alpha FG-GAP repeat containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000319918
InnateDB Gene IDBG-29556 (ITFG1)
Protein Structure
UniProt Annotation
Function Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}. Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitously expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TB96
PhosphoSite PhosphoSite-Q8TB96
TrEMBL H3BQ64
UniProt Splice Variant
Entrez Gene 81533
UniGene Hs.714051
RefSeq NP_110417
HUGO HGNC:30697
OMIM 611803
CCDS CCDS10728
HPRD 16692
IMGT
EMBL AC007494 AC007533 AC007599 AF212247 AF503339 AK027596 AK295228 AK299641 BC006321 BC024162
GenPept AAG41782 AAH06321 AAH24162 AAN31655 BAB55220 BAG58221 BAG61564

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca