InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COG3

Summary

InnateDB Protein

IDBP-29732.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COG3

Protein Name

component of oligomeric golgi complex 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000258654

InnateDB Gene

IDBG-29730 (COG3)

Protein Structure

UniProt Annotation

Function

Involved in ER-Golgi transport. {ECO:0000269PubMed:11929878}.

Subcellular Localization

Golgi apparatus, Golgi stack membrane {ECO:0000269PubMed:11292827}; Peripheral membrane protein {ECO:0000269PubMed:11292827}. Note=Associated with the peripheral membrane of cis/medial cisternae.

Disease Associations

Tissue Specificity

Widely expressed with highest levels in pancreas and testis and lowest levels in lung. {ECO:0000269PubMed:11292827}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.

Experimentally validated
Total	27 [view]
Protein-Protein	27 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0006486	protein glycosylation
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0006891	intra-Golgi vesicle-mediated transport
GO:0033365	protein localization to organelle
GO:0050821	protein stabilization

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005801	cis-Golgi network
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0017119	Golgi transport complex
GO:0032580	Golgi cisterna membrane