InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TMIE

Summary

InnateDB Protein

IDBP-30799.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TMIE

Protein Name

transmembrane inner ear

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000324775

InnateDB Gene

IDBG-30797 (TMIE)

Protein Structure

UniProt Annotation

Function

Unknown. The protein may play some role in a cellular membrane location. May reside within an internal membrane compartment and function in pathways such as those involved in protein and/or vesicle trafficking. Alternatively, the mature protein may be localized in the plasma membrane and serve as a site of interaction for other molecules through its highly charged C-terminal domain.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Deafness, autosomal recessive, 6 (DFNB6) [MIM:600971]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. {ECO:0000269PubMed:12145746}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Tissue Specificity

Expressed in many tissues. {ECO:0000269PubMed:12145746}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process