InnateDB Protein
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IDBP-31341.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SYCE2
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Protein Name
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synaptonemal complex central element protein 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000293695
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InnateDB Gene
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IDBG-31339 (SYCE2)
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Protein Structure
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Function |
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE1 in the central elements (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6PIF2
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PhosphoSite |
PhosphoSite-Q6PIF2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
256126
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UniGene |
Hs.655173
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RefSeq |
NP_001099048
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HUGO |
HGNC:27411
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OMIM |
611487
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CCDS |
CCDS42509
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HPRD |
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IMGT |
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EMBL |
AC092069
AD000092
AK302373
BC035819
CR746484
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GenPept |
AAH35819
BAG63695
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