Version 5.4
Homo sapiens Protein: LAPTM4A
Summary
InnateDB Protein IDBP-32074.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAPTM4A
Protein Name lysosomal protein transmembrane 4 alpha
Synonyms HUMORF13; LAPTM4; MBNT; Mtrp;
Species Homo sapiens
Ensembl Protein ENSP00000175091
InnateDB Gene IDBG-32070 (LAPTM4A)
Protein Structure
UniProt Annotation
Function May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=May reside in an intracellular membrane-bound compartment. {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004687 Lysosomal-associated transmembrane protein 4/5
IPR018396 Lysosomal-associated transmembrane protein, 4A/5
PFAM PF03821
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15012
PhosphoSite PhosphoSite-Q15012
TrEMBL Q6IBP4
UniProt Splice Variant
Entrez Gene 9741
UniGene Hs.467807
RefSeq NP_055528
HUGO HGNC:6924
OMIM
CCDS CCDS1696
HPRD 13959
IMGT
EMBL AC079145 AC098828 AY359028 BC000421 BC093075 CH471053 CR456758 D14696
GenPept AAH00421 AAH93075 AAQ89387 AAX88938 AAY24172 BAA03522 CAG33039 EAX00834 EAX00836

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca