Homo sapiens Protein: ASB7
Summary
InnateDB Protein IDBP-32101.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB7
Protein Name ankyrin repeat and SOCS box containing 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000328327
InnateDB Gene IDBG-32097 (ASB7)
Protein Structure
UniProt Annotation
Function Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 16 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001496 SOCS protein, C-terminal
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF07525
PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00253
SM00969
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H672
PhosphoSite PhosphoSite-Q9H672
TrEMBL A0A024RC94
UniProt Splice Variant
Entrez Gene 140460
UniGene Hs.708403
RefSeq NP_937886
HUGO HGNC:17182
OMIM 615052
CCDS CCDS10387
HPRD 10674
IMGT
EMBL AF451994 AK026204 AK289860 BC063581 CH471101
GenPept AAH63581 AAP97683 BAB15392 BAF82549 EAX02274 EAX02276 EAX02277