InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GIPC1

Summary

InnateDB Protein

IDBP-33392.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GIPC1

Protein Name

GIPC PDZ domain containing family, member 1

Synonyms

C19orf3; GIPC; GLUT1CBP; Hs.6454; IIP-1; NIP; RGS19IP1; SEMCAP; SYNECTIIN; SYNECTIN; TIP-2;

Species

Homo sapiens

Ensembl Protein

ENSP00000340698

InnateDB Gene

IDBG-33390 (GIPC1)

Protein Structure

UniProt Annotation

Function

May be involved in G protein-linked signaling.

Subcellular Localization

Cytoplasm. Membrane; Peripheral membrane protein.

Disease Associations

Tissue Specificity

Widely expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	52 [view]
Protein-Protein	51 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0017022	myosin binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0006605	protein targeting
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007268	synaptic transmission
GO:0014047	glutamate secretion
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031647	regulation of protein stability
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032467	positive regulation of cytokinesis
GO:0043542	endothelial cell migration
GO:0048167	regulation of synaptic plasticity

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005938	cell cortex
GO:0008021	synaptic vesicle
GO:0012506	vesicle membrane
GO:0016020	membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0043197	dendritic spine
GO:0043198	dendritic shaft
GO:0070062	extracellular vesicular exosome