InnateDB Protein
|
IDBP-33948.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
GRASP
|
Protein Name
|
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000293662
|
InnateDB Gene
|
IDBG-33946 (GRASP)
|
Protein Structure
|
|
Function |
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=Localized at postsynaptic membranes. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
2 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001478
PDZ domain
|
PFAM |
PF00595
PF13180
|
PRINTS |
|
PIRSF |
|
SMART |
SM00228
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q7Z6J2
|
PhosphoSite |
PhosphoSite-Q7Z6J2
|
TrEMBL |
F8VRX5
|
UniProt Splice Variant |
|
Entrez Gene |
160622
|
UniGene |
Hs.407202
|
RefSeq |
NP_859062
|
HUGO |
HGNC:18707
|
OMIM |
612027
|
CCDS |
CCDS8817
|
HPRD |
17077
|
IMGT |
|
EMBL |
AC025259
BC035500
BC052967
BC053666
|
GenPept |
AAH35500
AAH52967
AAH53666
|
|
|