Version 5.4
Homo sapiens Protein: EWSR1
Summary
InnateDB Protein IDBP-3492.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EWSR1
Protein Name Ewing sarcoma breakpoint region 1
Synonyms bK984G1.4; EWS;
Species Homo sapiens
Ensembl Protein ENSP00000331699
InnateDB Gene IDBG-3488 (EWSR1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 230 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.
Experimentally validated
Total 230 [view]
Protein-Protein 228 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 53 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR001876 Zinc finger, RanBP2-type
PFAM PF00076
PF00641
PRINTS
PIRSF
SMART SM00360
SM00547
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q01844
PhosphoSite PhosphoSite-Q01844
TrEMBL B0QYJ7
UniProt Splice Variant
Entrez Gene 2130
UniGene Hs.374477
RefSeq NP_001156758
HUGO HGNC:3508
OMIM 133450
CCDS CCDS54514
HPRD 00592
IMGT
EMBL AB016435 AC000026 AC002059 AK056309 AK056681 AL031186 BC000527 BC004817 BC011048 BC072442 CH471095 CR456490 X66899 X72990 X72991 X72992 X72993 X72994 X72995 X72996 X72997 X72998 X72999 X73000 X73001 X73002 X73003 X73004 Y07848 Y08806
GenPept AAH00527 AAH04817 AAH11048 AAH72442 BAA31990 BAB71145 BAB71252 CAA47350 CAA51489 CAA69177 CAA70044 CAG30376 CAI18001 CAQ10937 CAQ10938 CAQ10940 EAW59780 EAW59781 EAW59785 EAW59786 EAW59787

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca