Version 5.4
Homo sapiens Protein: RINT1
Summary
InnateDB Protein IDBP-35071.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RINT1
Protein Name RAD50 interactor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000257700
InnateDB Gene IDBG-35069 (RINT1)
Protein Structure
UniProt Annotation
Function Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control. {ECO:0000269PubMed:11096100, ECO:0000269PubMed:15272311, ECO:0000269PubMed:16600870}.
Subcellular Localization Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0031572 G2 DNA damage checkpoint
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR007528 RINT-1/TIP-1
PFAM PF04437
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NUQ1
PhosphoSite PhosphoSite-Q6NUQ1
TrEMBL
UniProt Splice Variant
Entrez Gene 60561
UniGene Hs.531388
RefSeq NP_068749
HUGO HGNC:21876
OMIM 610089
CCDS CCDS34726
HPRD 15250
IMGT
EMBL AC073073 AF317622 AK021847 BC007120 BC068483
GenPept AAG42101 AAH07120 AAH68483 AAQ96849 AAQ96850 BAB13910

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca