Version 5.4
Homo sapiens Protein: GSDMC
Summary
InnateDB Protein IDBP-35601.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GSDMC
Protein Name gasdermin C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000276708
InnateDB Gene IDBG-35599 (GSDMC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11223543}.
Disease Associations
Tissue Specificity Expressed primarily in trachea and spleen. {ECO:0000269PubMed:11223543}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005815 microtubule organizing center
Protein Structure and Domains
PDB ID
InterPro IPR007677 Gasdermin
PFAM PF04598
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BYG8
PhosphoSite PhosphoSite-Q9BYG8
TrEMBL
UniProt Splice Variant
Entrez Gene 56169
UniGene Hs.133244
RefSeq NP_113603
HUGO HGNC:7151
OMIM 608384
CCDS CCDS6360
HPRD 12222
IMGT
EMBL AB042405 AC022849 BC035321 BC063595
GenPept AAH35321 AAH63595 BAB40331

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca