InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC7A8

Summary

InnateDB Protein

IDBP-362101.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC7A8

Protein Name

solute carrier family 7 (amino acid transporter light chain, L system), member 8

Synonyms

LAT2; LPI-PC1;

Species

Homo sapiens

Ensembl Protein

ENSP00000391577

InnateDB Gene

IDBG-3104 (SLC7A8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015101	organic cation transmembrane transporter activity
GO:0015171	amino acid transmembrane transporter activity
GO:0015175	neutral amino acid transmembrane transporter activity
GO:0019534	toxin transporter activity
GO:0042605	peptide antigen binding

Biological Process

GO:0003333	amino acid transmembrane transport
GO:0006520	cellular amino acid metabolic process
GO:0006810	transport
GO:0006811	ion transport
GO:0006865	amino acid transport
GO:0007596	blood coagulation
GO:0009636	response to toxic substance
GO:0015695	organic cation transport
GO:0015804	neutral amino acid transport
GO:0050900	leukocyte migration
GO:0055065	metal ion homeostasis
GO:0055085	transmembrane transport
GO:1901998	toxin transport

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0070062	extracellular vesicular exosome