Version 5.4
Homo sapiens Protein: PMS2
Summary
InnateDB Protein IDBP-363474.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PMS2
Protein Name PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
Synonyms HNPCC4; PMS2CL; PMSL2;
Species Homo sapiens
Ensembl Protein ENSP00000392843
InnateDB Gene IDBG-7921 (PMS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
Experimentally validated
Total 54 [view]
Protein-Protein 51 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0032300 mismatch repair complex
Protein Structure and Domains
PDB ID
InterPro IPR003594 Histidine kinase-like ATPase, C-terminal domain
IPR013507 DNA mismatch repair protein, C-terminal
IPR014790 MutL, C-terminal, dimerisation
IPR020568 Ribosomal protein S5 domain 2-type fold
PFAM PF02518
PF13581
PF01119
PF08676
PRINTS
PIRSF
SMART SM00387
SM00853
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J167
UniProt Splice Variant
Entrez Gene 5395
UniGene Hs.632637
RefSeq
HUGO HGNC:9122
OMIM 600259
CCDS
HPRD 02598
IMGT
EMBL AC005995
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca