Version 5.4
Homo sapiens Protein: DDA1
Summary
InnateDB Protein IDBP-36390.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDA1
Protein Name DET1 and DDB1 associated 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000352928
InnateDB Gene IDBG-36388 (DDA1)
Protein Structure
UniProt Annotation
Function May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD- E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins. {ECO:0000269PubMed:17452440}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro IPR018276 Ubiquitin ligase, Det1/DDB1-complexing
PFAM PF10172
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BW61
PhosphoSite PhosphoSite-Q9BW61
TrEMBL A0A024R7J7
UniProt Splice Variant
Entrez Gene 79016
UniGene Hs.721286
RefSeq NP_076955
HUGO HGNC:28360
OMIM
CCDS CCDS12357
HPRD 15107
IMGT
EMBL AY563006 BC000615 CH471106 DQ090952
GenPept AAH00615 AAS66629 AAZ41375 EAW84593 EAW84594

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca