InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CRKL

Summary

InnateDB Protein

IDBP-364123.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRKL

Protein Name

v-crk sarcoma virus CT10 oncogene homolog (avian)-like

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000396646

InnateDB Gene

IDBG-1833 (CRKL)

Protein Structure

UniProt Annotation

Function

May mediate the transduction of intracellular signals.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 110 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	110 [view]
Protein-Protein	109 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005070	SH3/SH2 adaptor activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000186	activation of MAPKK activity
GO:0007254	JNK cascade
GO:0007265	Ras protein signal transduction
GO:0009967	positive regulation of signal transduction
GO:0035556	intracellular signal transduction
GO:0045087	innate immune response (InnateDB)
GO:0048011	neurotrophin TRK receptor signaling pathway