InnateDB Protein
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IDBP-366944.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NUSAP1
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Protein Name
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nucleolar and spindle associated protein 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000400746
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InnateDB Gene
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IDBG-7026 (NUSAP1)
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Protein Structure
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Function |
Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them. {ECO:0000250, ECO:0000269PubMed:12963707}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Chromosome {ECO:0000250}. Note=Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase (By similarity). Localizes to the mitotic spindle during anaphase and telophase then disappears from around the chromosomes during cytokinesis (By similarity). Localizes to multiple distinct regions of chromosomes throughout mitosis. {ECO:0000250, ECO:0000269PubMed:17276916, ECO:0000269PubMed:17618083}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
18
[view]
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Protein-Protein |
16
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BXS6
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PhosphoSite |
PhosphoSite-Q9BXS6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
51203
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UniGene |
Hs.615092
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RefSeq |
NP_060924
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HUGO |
HGNC:18538
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OMIM |
612818
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CCDS |
CCDS45236
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HPRD |
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IMGT |
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EMBL |
AC087721
AF090915
AF217513
AF290612
AF305711
AK023483
AK222819
AK293168
AL833611
BC001308
BC010838
BC012887
BC024772
CH471125
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GenPept |
AAF24034
AAF67624
AAG25874
AAH01308
AAH10838
AAH12887
AAH24772
AAK28023
BAB14586
BAD96539
BAG56712
EAW92483
EAW92486
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