Version 5.4
Homo sapiens Protein: MTOR
Summary
InnateDB Protein IDBP-368577.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTOR
Protein Name mechanistic target of rapamycin (serine/threonine kinase)
Synonyms FRAP; FRAP1; FRAP2; RAFT1; RAPT1;
Species Homo sapiens
Ensembl Protein ENSP00000398745
InnateDB Gene IDBG-89258 (MTOR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 230 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 230 [view]
Protein-Protein 226 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00454
PRINTS
PIRSF
SMART SM00146
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AKQ2
UniProt Splice Variant
Entrez Gene 2475
UniGene Hs.659634
RefSeq
HUGO HGNC:3942
OMIM 601231
CCDS
HPRD 03134
IMGT
EMBL AL049653 AL109811 AL391561
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca