Version 5.4
Homo sapiens Protein: POLR2B
Summary
InnateDB Protein IDBP-368687.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR2B
Protein Name polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
Synonyms hRPB140; hsRPB2; POL2RB; RPB2;
Species Homo sapiens
Ensembl Protein ENSP00000408638
InnateDB Gene IDBG-20530 (POLR2B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 94 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 94 [view]
Protein-Protein 93 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003899 DNA-directed RNA polymerase activity
GO:0032549 ribonucleoside binding
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007644 RNA polymerase, beta subunit, protrusion
PFAM PF04563
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JMN3
UniProt Splice Variant
Entrez Gene 5431
UniGene Hs.602757
RefSeq
HUGO HGNC:9188
OMIM 180661
CCDS
HPRD 15943
IMGT
EMBL AC069307
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca