Version 5.4
Homo sapiens Protein: HIBADH
Summary
InnateDB Protein IDBP-369418.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIBADH
Protein Name 3-hydroxyisobutyrate dehydrogenase
Synonyms NS5ATP1;
Species Homo sapiens
Ensembl Protein ENSP00000390205
InnateDB Gene IDBG-10662 (HIBADH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity
GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
GO:0051287 NAD binding
Biological Process
GO:0006098 pentose-phosphate shunt
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR011548 3-hydroxyisobutyrate dehydrogenase
PFAM PF03446
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 11112
UniGene Hs.599452
RefSeq
HUGO HGNC:4907
OMIM 608475
CCDS
HPRD 12238
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca