|
InnateDB Protein
|
IDBP-370520.4
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
WAS
|
|
Protein Name
|
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
|
|
Synonyms
|
IMD2; SCNX; THC; THC1; WASP;
|
|
Species
|
Homo sapiens
|
|
Ensembl Protein
|
ENSP00000410537
|
|
InnateDB Gene
|
IDBG-63703 (WAS)
|
|
Protein Structure
|
|
| Function |
|
| Subcellular Localization |
|
| Disease Associations |
|
| Tissue Specificity |
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
116
[view]
|
| Protein-Protein |
116
[view]
|
| Protein-DNA |
0
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
| Predicted by orthology |
| Total |
18 [view]
|
|
|
Molecular Function |
|
| Biological Process |
|
GO:0045087
|
innate immune response (InnateDB)
|
|
GO:2000601
|
positive regulation of Arp2/3 complex-mediated actin nucleation
|
|
| Cellular Component |
|
| PDB ID |
|
| InterPro |
IPR000697
WH1/EVH1
|
| PFAM |
PF00568
|
| PRINTS |
|
| PIRSF |
|
| SMART |
SM00461
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
|
| PhosphoSite |
PhosphoSite-
|
| TrEMBL |
C9J3B7
|
| UniProt Splice Variant |
|
| Entrez Gene |
7454
|
| UniGene |
Hs.602310
|
| RefSeq |
|
| HUGO |
HGNC:12731
|
| OMIM |
300392
|
| CCDS |
|
| HPRD |
02314
|
| IMGT |
|
| EMBL |
AF196970
|
| GenPept |
|
|
|
|
Version 5.4