InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CASP9

Summary

InnateDB Protein

IDBP-371034.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CASP9

Protein Name

caspase 9, apoptosis-related cysteine peptidase

Synonyms

APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56;

Species

Homo sapiens

Ensembl Protein

ENSP00000408691

InnateDB Gene

IDBG-90895 (CASP9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 75 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	75 [view]
Protein-Protein	72 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004197	cysteine-type endopeptidase activity
GO:0008234	cysteine-type peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0006915	apoptotic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001309 Peptidase C14, ICE, catalytic subunit p20
IPR002138 Peptidase C14, caspase non-catalytic subunit p10
IPR011600 Peptidase C14, caspase domain
IPR015917 Peptidase C14A, caspase precursor p45, core

PFAM

PF00656

PRINTS

PR00376

PIRSF

SMART

SM00115

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt