Version 5.4
Homo sapiens Protein: MLH1
Summary
InnateDB Protein IDBP-371078.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLH1
Protein Name mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Synonyms COCA2; FCC2; hMLH1; HNPCC; HNPCC2;
Species Homo sapiens
Ensembl Protein ENSP00000416476
InnateDB Gene IDBG-24600 (MLH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.
Experimentally validated
Total 151 [view]
Protein-Protein 144 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0005634 nucleus
GO:0032300 mismatch repair complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y806
UniProt Splice Variant
Entrez Gene 4292
UniGene Hs.195364
RefSeq
HUGO HGNC:7127
OMIM 120436
CCDS
HPRD 00390
IMGT
EMBL AC006583 AC011816 FJ940753
GenPept ACR33810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca