Homo sapiens Protein: INSL3
Summary
InnateDB Protein IDBP-37203.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INSL3
Protein Name insulin-like 3 (Leydig cell)
Synonyms ley-I-L; RLF; RLNL;
Species Homo sapiens
Ensembl Protein ENSP00000369017
InnateDB Gene IDBG-405522 (INSL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0002020 protease binding
GO:0005102 receptor binding
GO:0005158 insulin receptor binding
GO:0005179 hormone activity
Biological Process
GO:0001556 oocyte maturation
GO:0001701 in utero embryonic development
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007283 spermatogenesis
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0008584 male gonad development
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR016179 Insulin-like
PFAM PF00049
PRINTS
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51460
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 3640
UniGene Hs.741876
RefSeq NP_001252516
HUGO HGNC:6086
OMIM 146738
CCDS CCDS58655
HPRD 08854
IMGT
EMBL AC005952 AC007201 AK302780 AY082014 BC032810 BC053345 BC071706 BC106721 BC106722 CH471106 S72482 X73637
GenPept AAB31371 AAD22740 AAH32810 AAH53345 AAH71706 AAI06722 AAI06723 AAL92559 BAG63984 CAA52017 EAW84635