Version 5.4
Homo sapiens Protein: ZNF516
Summary
InnateDB Protein IDBP-372531.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF516
Protein Name zinc finger protein 516
Synonyms HsT287;
Species Homo sapiens
Ensembl Protein ENSP00000394757
InnateDB Gene IDBG-5184 (ZNF516)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation. May act as suppressor of replication stress and chromosome missegregation. {ECO:0000269PubMed:23446422}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92618
PhosphoSite PhosphoSite-Q92618
TrEMBL F5H2K2
UniProt Splice Variant
Entrez Gene 9658
UniGene Hs.725451
RefSeq NP_055458
HUGO HGNC:28990
OMIM 615114
CCDS CCDS74234
HPRD
IMGT
EMBL AC009716 AC018413 D86975
GenPept BAA13211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca