InnateDB Protein
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IDBP-372866.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATL2
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Protein Name
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atlastin GTPase 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000415336
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InnateDB Gene
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IDBG-46170 (ATL2)
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Protein Structure
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Function |
GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. {ECO:0000269PubMed:18270207, ECO:0000269PubMed:19665976}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:18270207}; Multi-pass membrane protein {ECO:0000269PubMed:18270207}.
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Disease Associations |
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Tissue Specificity |
Expressed in peripheral tissues (at protein level). {ECO:0000269PubMed:18270207}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003191
Guanylate-binding protein, C-terminal
IPR015894
Guanylate-binding protein, N-terminal
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF02841
PF02263
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NHH9
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PhosphoSite |
PhosphoSite-Q8NHH9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
64225
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UniGene |
Hs.727652
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RefSeq |
NP_071769
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HUGO |
HGNC:24047
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OMIM |
609368
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CCDS |
CCDS1795
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HPRD |
10662
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IMGT |
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EMBL |
AC016995
AF449176
AF449177
AF449178
AF449179
AF449180
AF449181
AF449182
AF449183
AF449184
AF449185
AF449186
AF449187
AK026946
AK225190
AK294049
AK302621
BC053508
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GenPept |
AAH53508
AAM97341
AAM97342
AAX88950
BAB15598
BAH11658
BAH13764
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