Version 5.4
Homo sapiens Protein: GMPR2
Summary
InnateDB Protein IDBP-3729.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GMPR2
Protein Name guanosine monophosphate reductase 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000334409
InnateDB Gene IDBG-3727 (GMPR2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003920 GMP reductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0009117 nucleotide metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:1902560 GMP reductase complex
Protein Structure and Domains
PDB ID
InterPro IPR000262 FMN-dependent dehydrogenase
IPR001093 IMP dehydrogenase/GMP reductase
IPR005993 Guanosine monophosphate reductase 1
PFAM PF01070
PF00478
PRINTS
PIRSF PIRSF000235
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q6PKC0
TrEMBL Q86SZ5
UniProt Splice Variant
Entrez Gene 51292
UniGene Hs.368855
RefSeq
HUGO HGNC:4377
OMIM 610781
CCDS
HPRD 13590
IMGT
EMBL AL096870 BX161518 CH471078
GenPept CAD61951 EAW66058

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca