Version 5.4
Homo sapiens Protein: NR1H3
Summary
InnateDB Protein IDBP-373087.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NR1H3
Protein Name nuclear receptor subfamily 1, group H, member 3
Synonyms LXR-a; LXRA; RLD-1;
Species Homo sapiens
Ensembl Protein ENSP00000412636
InnateDB Gene IDBG-42877 (NR1H3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
Experimentally validated
Total 51 [view]
Protein-Protein 45 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001628 Zinc finger, nuclear hormone receptor-type
IPR023257 Liver X receptor
PFAM PF00105
PRINTS PR00047
PR02034
PIRSF
SMART SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J2C8
UniProt Splice Variant
Entrez Gene 10062
UniGene Hs.438863
RefSeq
HUGO HGNC:7966
OMIM 602423
CCDS
HPRD 07211
IMGT
EMBL AC018410
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca