Version 5.4
Homo sapiens Protein: CCPG1
Summary
InnateDB Protein IDBP-373270.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCPG1
Protein Name DYX1C1-CCPG1 readthrough (non-protein coding)
Synonyms CPR8;
Species Homo sapiens
Ensembl Protein ENSP00000415128
InnateDB Gene IDBG-735442 (CCPG1)
Protein Structure
UniProt Annotation
Function Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. {ECO:0000250, ECO:0000269PubMed:9383053}.
Subcellular Localization Cytoplasmic granule membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007049 cell cycle
GO:0008284 positive regulation of cell proliferation
GO:0045787 positive regulation of cell cycle
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ULG6
PhosphoSite PhosphoSite-Q9ULG6
TrEMBL H3BTZ1
UniProt Splice Variant
Entrez Gene 9236
UniGene Hs.733891
RefSeq NP_001191380
HUGO HGNC:24227
OMIM 611326
CCDS CCDS55967
HPRD 09895
IMGT
EMBL AB033080 AC013355 AC018926 AF011794 AF212228 AK022459 AK292795 BC015203 BC029398 BC034914 BC039871 CH471082
GenPept AAB69314 AAH15203 AAH29398 AAH34914 AAH39871 AAK14914 BAA86568 BAB14042 BAF85484 EAW77481

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca