Version 5.4
Homo sapiens Protein: BORA
Summary
InnateDB Protein IDBP-37380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BORA
Protein Name bora, aurora kinase A activator
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000375082
InnateDB Gene IDBG-37374 (BORA)
Protein Structure
UniProt Annotation
Function Required for the activation of AURKA at the onset of mitosis. {ECO:0000269PubMed:16890155}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0007088 regulation of mitosis
GO:0032880 regulation of protein localization
GO:0060236 regulation of mitotic spindle organization
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR023252 Aurora borealis protein
PFAM PF15280
PRINTS PR02038
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PGQ7
PhosphoSite PhosphoSite-Q6PGQ7
TrEMBL B5LMG6
UniProt Splice Variant
Entrez Gene 79866
UniGene Hs.743339
RefSeq NP_079084
HUGO HGNC:24724
OMIM 610510
CCDS CCDS9446
HPRD 13389
IMGT
EMBL AK026277 AL138695 BC007119 BC025367 BC044213 BC056876 CH471093 EU834129
GenPept AAH07119 AAH25367 AAH44213 AAH56876 ACH72049 BAB15426 CAH72712 CAH72713 EAW80514

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca