Version 5.4
Homo sapiens Protein: MCM5
Summary
InnateDB Protein IDBP-374267.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCM5
Protein Name minichromosome maintenance complex component 5
Synonyms CDC46; P1-CDC46;
Species Homo sapiens
Ensembl Protein ENSP00000408705
InnateDB Gene IDBG-5405 (MCM5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 104 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 104 [view]
Protein-Protein 97 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001208 Mini-chromosome maintenance, DNA-dependent ATPase
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF00493
PRINTS PR01657
PIRSF
SMART SM00350
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AHB2
UniProt Splice Variant
Entrez Gene 4174
UniGene Hs.607034
RefSeq
HUGO HGNC:6948
OMIM 602696
CCDS
HPRD 04075
IMGT
EMBL Z82244
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca