Version 5.4
Homo sapiens Protein: TMCO3
Summary
InnateDB Protein IDBP-374343.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMCO3
Protein Name transmembrane and coiled-coil domains 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000389399
InnateDB Gene IDBG-53356 (TMCO3)
Protein Structure
UniProt Annotation
Function Probable Na(+)/H(+) antiporter. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015299 solute:proton antiporter activity
Biological Process
GO:0006812 cation transport
GO:0055085 transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006153 Cation/H+ exchanger
PFAM PF00999
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UWJ1
PhosphoSite PhosphoSite-Q6UWJ1
TrEMBL A0A024RE09
UniProt Splice Variant
Entrez Gene 55002
UniGene Hs.596088
RefSeq NP_060375
HUGO HGNC:20329
OMIM
CCDS CCDS9537
HPRD 12612
IMGT
EMBL AF209505 AK000630 AK074415 AL442125 AY358768 BC012564 BC068515 CH471085
GenPept AAH12564 AAH68515 AAM92892 AAQ89128 BAA91295 BAB85074 CAI39784 CAI39785 EAX09212 EAX09215

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca