InnateDB Protein
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IDBP-374359.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZMIZ2
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Protein Name
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zinc finger, MIZ-type containing 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000414723
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InnateDB Gene
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IDBG-15128 (ZMIZ2)
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Protein Structure
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Function |
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. {ECO:0000269PubMed:16051670}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:16051670, ECO:0000269PubMed:9853615}. Note=Detected at replication foci throughout S phase.
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Disease Associations |
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Tissue Specificity |
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. {ECO:0000269PubMed:16051670}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
15
[view]
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Protein-Protein |
15
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0008270
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zinc ion binding
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GO:0030374
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ligand-dependent nuclear receptor transcription coactivator activity
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
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InterPro |
IPR004181
Zinc finger, MIZ-type
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PFAM |
PF02891
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NF64
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PhosphoSite |
PhosphoSite-Q8NF64
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TrEMBL |
C9JDA5
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UniProt Splice Variant |
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Entrez Gene |
83637
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UniGene |
Hs.77978
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RefSeq |
XP_005249923
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HUGO |
HGNC:22229
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OMIM |
611196
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CCDS |
CCDS43576
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HPRD |
13225
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IMGT |
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EMBL |
AB015330
AB067473
AC004859
AC013436
AK090415
AK090841
AL136572
AL831933
AY426594
BC021924
BC110435
CH236960
CH471128
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GenPept |
AAH21924
AAI10436
AAP22368
AAR85526
BAA34789
BAB67779
BAC03396
BAG52237
CAB66507
CAH56269
EAL23750
EAW61083
EAW61084
EAW61085
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