Version 5.4
Homo sapiens Protein: RAP1GDS1
Summary
InnateDB Protein IDBP-374692.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAP1GDS1
Protein Name RAP1, GTP-GDP dissociation stimulator 1
Synonyms GDS1; SmgGDS;
Species Homo sapiens
Ensembl Protein ENSP00000407157
InnateDB Gene IDBG-30852 (RAP1GDS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 42 [view]
Protein-Protein 42 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
GO:0051561 positive regulation of mitochondrial calcium ion concentration
Cellular Component
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000225 Armadillo
IPR016024 Armadillo-type fold
PFAM PF00514
PRINTS
PIRSF
SMART SM00185
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P52306
PhosphoSite PhosphoSite-P52306
TrEMBL
UniProt Splice Variant
Entrez Gene 5910
UniGene Hs.701182
RefSeq NP_066982
HUGO HGNC:9859
OMIM 179502
CCDS CCDS47106
HPRD 11763
IMGT
EMBL AC019077 AC058823 AC078961 AF215923 AF237413 BC001816 BC001851 BC098269 BC098334 BC099708 BC099845 BT006837 CH471057 X63465
GenPept AAF32290 AAF43211 AAH01816 AAH01851 AAH98269 AAH98334 AAH99708 AAH99845 AAP35483 CAA45067 EAX06069 EAX06071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca