InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IKZF1

Summary

InnateDB Protein

IDBP-375212.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IKZF1

Protein Name

IKAROS family zinc finger 1 (Ikaros)

Synonyms

Hs.54452; IK1; IKAROS; LyF-1; LYF1; PPP1R92; PRO0758; ZNFN1A1;

Species

Homo sapiens

Ensembl Protein

ENSP00000401507

InnateDB Gene

IDBG-16397 (IKZF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	59 [view]
Protein-Protein	52 [view]
Protein-DNA	7 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0007049	cell cycle
GO:0007498	mesoderm development
GO:0016568	chromatin modification

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR015880 Zinc finger, C2H2-like

PFAM

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13422

PhosphoSite

PhosphoSite-Q13422

TrEMBL

UniProt Splice Variant

Entrez Gene

10320

UniGene

Hs.739003

RefSeq

NP_001207704

HUGO

HGNC:13176

OMIM

603023

CCDS

HPRD

04318

IMGT

EMBL

AC124014 AC233268 AK303586 AY377974 BC018349 BT009836 CH236955 CH471128 S80876 U40462

GenPept

AAB50683 AAC50459 AAH18349 AAP88838 AAR84585 BAG64603 EAL23900 EAW60977 EAW60978 EAW60979 EAW60981