InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDC

Summary

InnateDB Protein

IDBP-375273.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDC

Protein Name

dopa decarboxylase (aromatic L-amino acid decarboxylase)

Synonyms

AADC;

Species

Homo sapiens

Ensembl Protein

ENSP00000395069

InnateDB Gene

IDBG-16596 (DDC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004058	aromatic-L-amino-acid decarboxylase activity
GO:0005515	protein binding
GO:0016829	lyase activity
GO:0016831	carboxy-lyase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0006520	cellular amino acid metabolic process
GO:0019752	carboxylic acid metabolic process
GO:0034641	cellular nitrogen compound metabolic process
GO:0042416	dopamine biosynthetic process
GO:0042423	catecholamine biosynthetic process
GO:0044281	small molecule metabolic process
GO:0046219	indolalkylamine biosynthetic process

Cellular Component

GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase
IPR002129 Pyridoxal phosphate-dependent decarboxylase
IPR010977 Aromatic-L-amino-acid decarboxylase
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF01212
PF00282

PRINTS

PR00800

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P20711