Version 5.4
Homo sapiens Protein: EGFR
Summary
InnateDB Protein IDBP-375789.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EGFR
Protein Name epidermal growth factor receptor
Synonyms ERBB; ERBB1; HER1; mENA; PIG61;
Species Homo sapiens
Ensembl Protein ENSP00000413354
InnateDB Gene IDBG-16933 (EGFR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 800 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 800 [view]
Protein-Protein 790 [view]
Protein-DNA 9 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000494 EGF receptor, L domain
PFAM PF01030
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JYS6
UniProt Splice Variant
Entrez Gene 1956
UniGene Hs.731652
RefSeq
HUGO HGNC:3236
OMIM 131550
CCDS
HPRD 00579
IMGT
EMBL AC006977 AC073324
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca