InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC26A6

Summary

InnateDB Protein

IDBP-376304.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC26A6

Protein Name

solute carrier family 26, member 6

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000401066

InnateDB Gene

IDBG-304554 (SLC26A6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005254	chloride channel activity
GO:0005515	protein binding
GO:0008271	secondary active sulfate transmembrane transporter activity
GO:0015106	bicarbonate transmembrane transporter activity
GO:0015108	chloride transmembrane transporter activity
GO:0015116	sulfate transmembrane transporter activity
GO:0015301	anion:anion antiporter activity
GO:0015499	formate transmembrane transporter activity
GO:0015562	efflux transmembrane transporter activity
GO:0015659	formate uptake transmembrane transporter activity
GO:0015660	formate efflux transmembrane transporter activity
GO:0019531	oxalate transmembrane transporter activity
GO:0030165	PDZ domain binding

Biological Process

GO:0006811	ion transport
GO:0006820	anion transport
GO:0006821	chloride transport
GO:0008272	sulfate transport
GO:0015701	bicarbonate transport
GO:0015724	formate transport
GO:0015797	mannitol transport
GO:0019532	oxalate transport
GO:0030321	transepithelial chloride transport
GO:0038166	angiotensin-activated signaling pathway
GO:0042045	epithelial fluid transport
GO:0046724	oxalic acid secretion
GO:0048240	sperm capacitation
GO:0050892	intestinal absorption
GO:0051453	regulation of intracellular pH
GO:0051454	intracellular pH elevation
GO:0055085	transmembrane transport
GO:0070528	protein kinase C signaling
GO:0070633	transepithelial transport
GO:0071320	cellular response to cAMP
GO:0071332	cellular response to fructose stimulus
GO:0071346	cellular response to interferon-gamma
GO:1902358	sulfate transmembrane transport
GO:1902476	chloride transmembrane transport
GO:2001150	positive regulation of dipeptide transmembrane transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0012506	vesicle membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0031526	brush border membrane
GO:0031988	membrane-bounded vesicle
GO:0034707	chloride channel complex
GO:0097225	sperm midpiece