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InnateDB Protein
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IDBP-376697.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TEX10
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Protein Name
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testis expressed 10
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000399872
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InnateDB Gene
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IDBG-78750 (TEX10)
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Protein Structure
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| Function |
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {ECO:0000269PubMed:22872859}.
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| Subcellular Localization |
Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus membrane {ECO:0000269PubMed:12429849}; Multi-pass membrane protein {ECO:0000269PubMed:12429849}. Nucleus, nucleolus {ECO:0000269PubMed:12429849}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
23
[view]
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| Protein-Protein |
22
[view]
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| Protein-DNA |
1
[view]
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
1 [view]
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q9NXF1
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
54881
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| UniGene |
Hs.494648
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| RefSeq |
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| HUGO |
HGNC:25988
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| OMIM |
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| CCDS |
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| HPRD |
15489
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4