Version 5.4
Homo sapiens Protein: PTK2
Summary
InnateDB Protein IDBP-377047.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTK2
Protein Name PTK2 protein tyrosine kinase 2
Synonyms FADK; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71;
Species Homo sapiens
Ensembl Protein ENSP00000403416
InnateDB Gene IDBG-37147 (PTK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 166 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 166 [view]
Protein-Protein 165 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004713 protein tyrosine kinase activity
GO:0004871 signal transducer activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007172 signal complex assembly
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR005189 Focal adhesion kinase, targeting (FAT) domain
PFAM PF03623
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RJQ2
UniProt Splice Variant
Entrez Gene 5747
UniGene Hs.736231
RefSeq
HUGO HGNC:9611
OMIM 600758
CCDS
HPRD 02859
IMGT
EMBL AC067931 AC100860 AC105009 AC105235 AK301557
GenPept BAG63053

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca