Version 5.4
Homo sapiens Protein: FXYD3
Summary
InnateDB Protein IDBP-377640.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FXYD3
Protein Name FXYD domain containing ion transport regulator 3
Synonyms MAT8; PLML;
Species Homo sapiens
Ensembl Protein ENSP00000389770
InnateDB Gene IDBG-43497 (FXYD3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005254 chloride channel activity
Biological Process
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000272 Ion-transport regulator, FXYD motif
PFAM PF02038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14802
PhosphoSite PhosphoSite-Q14802
TrEMBL
UniProt Splice Variant
Entrez Gene 5349
UniGene
RefSeq NP_068710
HUGO HGNC:4027
OMIM 604996
CCDS CCDS12443
HPRD 05410
IMGT
EMBL AC020907 BC005238 BC090044 BT006712 BU157560 CR456945 CR542197 U28249 X93036
GenPept AAA73922 AAH05238 AAH90044 AAP35358 CAA63604 CAG33226 CAG46994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca