Version 5.4
Homo sapiens Protein: PIBF1
Summary
InnateDB Protein IDBP-37844.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIBF1
Protein Name progesterone immunomodulatory binding factor 1
Synonyms C13orf24; CEP90; PIBF;
Species Homo sapiens
Ensembl Protein ENSP00000317144
InnateDB Gene IDBG-37840 (PIBF1)
Protein Structure
UniProt Annotation
Function Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon. {ECO:0000269PubMed:11935316}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005813 centrosome
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR010989 t-SNARE
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WXW3
PhosphoSite PhosphoSite-Q8WXW3
TrEMBL
UniProt Splice Variant
Entrez Gene 10464
UniGene Hs.604356
RefSeq NP_006337
HUGO HGNC:23352
OMIM 607532
CCDS CCDS31991
HPRD 06337
IMGT
EMBL AF330046 AL354720 AL391384 AY370776 AY375528 BC051911 Y09631
GenPept AAH51911 AAL37481 AAQ67659 AAQ73282 CAA70844 CAI14869 CAI15673

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca