Homo sapiens Protein: HEMK1 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-378589.4 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | HEMK1 | ||||||||||
Protein Name | HemK methyltransferase family member 1 | ||||||||||
Synonyms | |||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Protein | ENSP00000404334 | ||||||||||
InnateDB Gene | IDBG-37141 (HEMK1) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L. {ECO:0000269PubMed:18541145}. | ||||||||||
Subcellular Localization | Mitochondrion {ECO:0000269PubMed:18541145}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR000241
Putative RNA methylase domain IPR002295 N6 adenine-specific DNA methyltransferase, D21 class IPR004398 RNA methyltransferase, RsmD IPR004556 Modification methylase HemK IPR007848 Methyltransferase small domain IPR010456 Ribosomal L11 methyltransferase, PrmA IPR013216 Methyltransferase type 11 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like |
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PFAM |
PF01170
PF03602 PF05175 PF06325 PF08241 |
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PRINTS |
PR00506
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PIRSF |
PIRSF015855
PIRSF004553 |
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SMART | |||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9Y5R4 | ||||||||||
PhosphoSite | PhosphoSite-Q9Y5R4 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 51409 | ||||||||||
UniGene | Hs.517987 | ||||||||||
RefSeq | XP_005265276 | ||||||||||
HUGO | HGNC:24923 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS2830 | ||||||||||
HPRD | 13645 | ||||||||||
IMGT | |||||||||||
EMBL | AF131220 AF172244 BC000781 | ||||||||||
GenPept | AAD26417 AAD51328 AAH00781 | ||||||||||