Homo sapiens Protein: CSTF1
Summary
InnateDB Protein IDBP-378998.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSTF1
Protein Name cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
Synonyms CstF-50; CstFp50;
Species Homo sapiens
Ensembl Protein ENSP00000387968
InnateDB Gene IDBG-81876 (CSTF1)
Protein Structure
UniProt Annotation
Function One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 17 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q05048
TrEMBL A3KFI9
UniProt Splice Variant
Entrez Gene 1477
UniGene Hs.172865
RefSeq
HUGO HGNC:2483
OMIM 600369
CCDS
HPRD 02653
IMGT
EMBL AL121914
GenPept